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Alfredo Giménez-Cassina Selected Research

SAG compound

4/2022The smoothened agonist SAG reduces mitochondrial dysfunction and neurotoxicity of frataxin-deficient astrocytes.

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Alfredo Giménez-Cassina Research Topics

Disease

2Friedreich Ataxia (Friedreich's Ataxia)
04/2022 - 06/2007
2Mitochondrial Diseases (Mitochondrial Disease)
04/2022 - 12/2012
2Seizures (Absence Seizure)
01/2021 - 05/2012
1Nervous System Heredodegenerative Disorders
04/2022
1Lactic Acidosis
01/2019
1Cognitive Dysfunction
10/2018
1Postoperative Cognitive Complications
10/2018
1Epilepsy (Aura)
11/2017
1Nervous System Diseases (Neurological Disorders)
11/2017
1B-Cell Lymphoma (Lymphoma, B Cell)
04/2015
1Insulin Resistance
02/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2012
1Infections
06/2007
1Neuroblastoma
11/2003
1Alzheimer Disease (Alzheimer's Disease)
11/2003

Drug/Important Bio-Agent (IBA)

2FrataxinIBA
04/2022 - 06/2007
2Adenosine Triphosphate (ATP)IBA
01/2021 - 05/2012
2Glycogen Synthase Kinase 3IBA
12/2012 - 11/2003
2Glucose (Dextrose)FDA LinkGeneric
12/2012 - 05/2012
1Mitochondrial Proteins (Mitochondrial Protein)IBA
04/2022
1SAG compoundIBA
04/2022
1Ketone BodiesIBA
01/2021
1Biological ProductsIBA
01/2021
1Pyruvic Acid (Pyruvate)IBA
01/2019
1Methionine (L-Methionine)FDA Link
01/2019
1CarbonIBA
11/2017
1Proteins (Proteins, Gene)FDA Link
04/2015
1LeptinIBA
02/2014
1Protein Kinases (Protein Kinase)IBA
12/2012
1Nerve Growth Factors (Neurotrophins)IBA
12/2012
1Brain-Derived Neurotrophic Factor (BDNF)IBA
12/2012
1HexokinaseIBA
12/2012
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
11/2003
1N- (4- methoxybenzyl)- N'- (5- nitro- 1,3- thiazol- 2- yl)ureaIBA
11/2003
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2003
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
11/2003

Therapy/Procedure

1Ketogenic Diet
01/2021
1Therapeutics
10/2018